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CME: Chronic Idiopathic Constipation (CIC): Optimizing Pharmacotherapeutic Management Strategies


Program Description / Statement of Need:


Chronic idiopathic constipation (CIC) is a clinical condition comprised of a myriad of etiologies and subgroup that affects between fourteen and 28 percent of the U.S. population. Not only is it prevalent, but it is also expensive; it results in anywhere between two and a half and seven million healthcare visits each year at a cost of $29 billion. In spite of its widespread impact, it is thought to be underreported due to social perceptions and lack of a clear-cut definition for constipation. Symptoms may arise: as a result of poor nutrition, sedentary lifestyle, demographic predisposition; secondary to an adverse drug effect; from neuropsychiatric conditions; or completely idiopathically.




  • Daily intestinal fluid balance
  • Salivary and succus enterricus composition
  • Anatomical and physiological review
  • Rome IV Criteria
  • Primary and secondary causes of constipation
  • Physical exam
  • Colorectal structure and motility
  • Diagnosis of chronic constipation
  • Treatments: bulk forming laxatives, osmotic laxatives, stimulant laxatives, emollients & surfactants, chloride channel activator, uroguanylin analog
  • Food diversity
  • The microbiome


Target Audience:

The following healthcare professionals: gastroenterologists and primary care physicians; physician assistants, nurse practitioners, nurses, and pharmacists who practice in gastroenterology; and any other healthcare professionals with an interest in or who clinically encounter patients with chronic idiopathic constipation.

Program Objectives:

By the end of the session the participant will be able to:

    • Describe the pathophysiology of chronic idiopathic constipation
    • Describe the benefits and risks of pharmacotherapy for chronic idiopathic constipation and take them into account when formulating a treatment plan for different patients
    • Formulate an evidence-based treatment plan for a variety of patients with chronic idiopathic constipation.
    • Recommend therapy changes in patients with chronic idiopathic constipation who do not respond to a previously prescribed treatment


    This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education through ScientiaCME. ScientiaCME is accredited by the ACCME to provide continuing medical education for physicians.


    Credit Designation: ScientiaCME designates this educational activity for a maximum of  1 AMA PRA Category 1 Credit(s)™ toward the AMA Physician's Recognition Award. Physicians should only claim credit commensurate with the extent of their participation in the activity.




    ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmaceutical education. This program is approved for 1.0 hours (0.1 CEUs) of continuing education.  Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test.   Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit.  ACPE # 0574-0000-17-039-H01-P.  ACPE Accreditation effective 10/2/17, expires 10/2/19. 

    This is a Knowledge (K)-type activity.

    Release Date: October 02, 2017
    Expiration Date: October 02, 2019

    Faculty: Joseph Weiss MD

    Faculty Disclosure and Resolution of COI:

     As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.


    Faculty Disclosure:   Joseph Weiss, MD, FACP, FACG, AGAF,  Clinical Professor of Medicine University of California, San Diego has no relevant conflicts of interest to disclose.


    Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP has no relevant conflicts of interest to disclose.


    Commercial Support Disclosure: This program is supported by an educational grant from Synergy Pharmaceuticals

    Additional Courses That Are Related To This Course

    Therapeutic updates and best practices in the treatment of irritable bowel syndrome with constipation (IBS-C)


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    -Read the learning objectives and faculty disclosures above

    -Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowedge gained by participating in this CME activity.

    -View the on-line program. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.

    -Take the post-test

    -Complete the program evaluation and CME registration. A CE certificate will be emailed to you.

    Perform Pre-Test (optional)
    Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

    Download the Presentation (optional)


    View the online program


    Perform Post-Test

    Complete the Symposium Evaluation and Request CE Certificate

This program is supported by an educational grant from Synergy Pharmaceuticals


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