In this online CME self-learning program:
Growth hormone deficiency (GHD), a condition characterized by inadequate endogenous production. When its onset occurs in adulthood, the etiology is related predominantly to oncologic causes (or their attendant treatment) in the vast majority of cases. In the United States, more than 50,000 adults are estimated to be growth hormone deficient, and 6,000 new cases are reported each year, inclusive of children with GHD who transition to adulthood (the prevalence of pediatric GHD is estimated to be between 1 in 4,000 and 1 in 10,000).
The classification of GHD depends on the underlying pathology and stems from one or more of the following: the inability of the pituitary gland to produce growth hormone (pituitary or classic); the failure of the hypothalamus to produce and/or transmit the messaging hormone growth hormone releasing hormone (GHRH) (hypothalamic GHD); the failure of other hormonal/metabolic functions caused by various or unknown etiologies that lead to pituitary failure to produce, uptake or utilize GH (functional GHD); and when the cause is unknown, it is characterized as idiopathic GHD. With respect to secondary causes, GHD may result from congenital genetic disorders, tumors, infections, radiation, trauma, psychosocial deprivation, hypothyroidism, poorly controlled diabetes mellitus, hormonal treatments, certain drugs, malnutrition, nutritional malabsorption, or gastrointestinal disorders.
A review primer: epidemiologic, pathophysiologic, etiologic features, and clinical signs and symptoms
Treatment options available for acromegaly
Summary, conclusions, and best practice recap
Healthcare professionals specializing in: endocrinology and those who otherwise commonly care for or clinically encounter adult patients with GHD.
This program is supported by an educational grant from Novo Nordisk.
Release Date: July 12, 2016 -- Expiration Date: July 12, 2018
Faculty: Julie Silverstein, MD
By the end of the session the participant will be able to:
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Faculty Disclosure: Dr. Julie Silverstein, MD, Assistant Professor of Medicine & Neurological Surgery Medical Director Pituitary Center Washington University School of Medicine has Pfizer, Novartis, and Novo Nordisk financial relationships to disclose.
Disclosures of Educational Planners: Charles Turck, PharmD is an officer and part owner of ScientiaCME, LLC with no relevent financial disclosures.
Commercial Support Disclosure: This program is supported by an educational grant from Novo Nordisk.
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