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CME: Updates in the management of insomnia: Therapeutic updates and optimizing treatment

Activity Description / Statement of Need:

In this online, self-learning activity:

Insomnia is defined by the dissatisfaction of sleep quality or quantity characterized by having difficulty falling asleep, staying asleep, waking too early, or a combination of these. It is defined as chronic if the condition persists for three months, despite the opportunity for sleep or eradication of external stimulus. Insomnia affects people of all ages, though the likelihood of developing insomnia increases with age: reporting one-third of the adult population having been affected by at least one symptom of insomnia.

This learning activity has been designed to bring healthcare professionals’ knowledge of the strategies for treatment of insomnia up to date and to improve their competence and performance in treating it. The activity will also focus on the role of novel pharmacotherapies in the management of insomnia.

Target Audience:

The following HCPs: neurologists, psychiatrists, sleep medicine specialists, and primary care physicians; physician assistants, nurse practitioners, nurses, and pharmacists who practice in the aforementioned areas of specialty; and those who otherwise have an interest in or commonly care for or clinically encounter patients with insomnia.

Commercial Support Disclosure: This activity is supported by an educational grant from Eisai.

Learners may participate in this activity free of charge.

Release Date: October 18, 2019 -- Expiration Date: October 18, 2021

Faculty: Terese Hammond, MD



Faculty introductions, disclosures

Introduction content: cursory refresher and review of insomnia

  • Epidemiology
  • Pathophysiology and risk factors
  • Complications
  • Impact on quality-of-life (QoL)
  • Economic burden

Treatment of insomnia

  • Non-pharmacologic:
  • Sleep hygiene optimization
  • CBT
  • Present therapy: roles and limitations
  • Pharmacologic

– GABA agonists

– Selective melatonin receptor agonist

  • Emerging therapies

– Orexin receptor antagonists

  • First- and later-line therapies, including treatment-refractory cases
  • Clinical pearls and barriers to care
  • Patient case(s)

Conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Describe the pathophysiology of insomnia such that it might inform treatment mechanisms
  • Identify the currently available and emerging pharmacotherapeutic treatments for management of insomnia and apply them to patient cases using evidence-based medicine
  • Evaluate a treatment plan for a specific patient with insomnia to optimize safety and efficacy, suggesting modifications for improvement
  • Describe barriers to care associated with treating patients with insomnia


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through ScientiaCME. ScientiaCME is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation: ScientiaCME designates this educational activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™ toward the AMA Physician's Recognition Award. Physicians should only claim credit commensurate with the extent of their participation in the activity.

PhysiciansFor maintenance of certification (MOC) credit, you must enter your board certification ID # and birth date correctly.  It is the learner's responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive MOC credit for this activity. Please note: not all activities on this site provide MOC credit. If this activity does not specify that it provides MOC credit in this section, then it does NOT provide MOC credit.


ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 1.0 contact hours (0.1 CEUs) of continuing pharmacy education credit. Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test. Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit.  ACPE # 0574-0000-19-044-H01-P. ACPE accreditation effective 10/19/19 and expires 10/19/21. This is a Application (A)-type activity.

PharmacistsYou must enter your NABP # and birth date correctly so that proof of participation can be posted to your NABP CPE profile. It is the learner's responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive CPE credit for this activity.

Nurse Practitioners (NPs): The American Academy of Nurse Practitioners accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.  ScientiaCME will provide NPs who successfully complete each activity with a certificate of participation indicating that the activity was designated for AMA PRA Category 1 Credit(s)™.

Physician Assistants: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.

Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.

Faculty Disclosure: Terese Hammond, MD , has no relevant financial disclosures.

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant financial disclosures.



  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowedge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Take the post-test
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural and Linguistic Competence

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

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Addressing barriers to optimal care in schizophrenia with pharmacotherapy