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CME: Opioid dependence and opioid use disorder: Best practices, barriers in care, and the role of long-acting injectable medication


Activity Description / Statement of Need:

In this online, self-learning activity:

Opioid use disorder (OUD) affects millions of individuals globally and is best defined by the Diagnostic and Statistic Manual of Mental Disorders, Fifth Edition (DSM-5) as a condition due to tolerance, manifestation of physical dependence, and loss of control leading to health hazards.The scale of the problem is staggering, and while the causes are manifold, it is fueled in part by widespread availability: the Centers for Disease Control and Prevention estimates that the distribution of prescription opioid analgesics rose over fivefold between 1997 and 2007 and that there are enough opioid equivalents presently to allow for every American to take five milligrams of hydrocodone six times a day for three weeks straight.

Target Audience:

Healthcare professionals specializing in: addiction specialists, pain management specialists, primary care physicians, and psychiatrists; physician assistants, nurse practitioners, nurses, and pharmacists who practice in pain management or substance abuse; and any other health professionals who encounter OUD in the clinical setting.

Commercial Support Disclosure: This activity is supported by an educational grant from Alkermes.

Learners may participate in this activity free of charge.

Release Date: December 30, 2019 -- Expiration Date: December 30, 2021

Faculty: Richard Shih, MD


Faculty introduction, disclosures

Primer on OUD’s epidemiology, what is known about the neuropathophysiology, risk factors, and psychosocial impact

  • Statistics – snapshots and trends
  • Incidence and significance of inappropriate selection and treatment of opioid therapy and relation to opioid deaths
  • Impact on the patient level and on society
  • Adults and pediatrics

Treatment of OUD

  • Therapeutic modalities
  • Medical therapy and the role of long-acting injectables
  • Psychological counseling
  • Adult vs. pediatric perspective
  • Special patient populations: pregnancy, incarceration
  • Best practice: implementation and selection of treatment
  • Dosage forms and adherence to therapy
  • Patient case(s)

Summary, conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Describe the epidemiology of OUD and dependence, and outline current and the significance of inappropriate selection and treatment of opioid therapy
  • Identify long-acting treatment modalities for OUD and dependence, and apply them to patient cases using evidence-based medicine
  • Identify challenges associated with the selection and implementation of drug regimens to the treatment of OUD and dependence, including risk factors for opioid overdose
  • Develop strategies for recognizing and improving therapeutic adherence in patients treated for OUD and opioid dependence


ACCME Activity #201379550


Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.

Faculty Disclosure: Richard Shih, MD, Professor of Emergency Medicine, Schmidt College of Medicine, has no relevant financial disclosures.

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant financial disclosures.



  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Minimum participation threshold: Take the post-test. A score of 70% or higher is required to pass and proceed to the activity evaluation.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural/Linguistic Competence & Health Disparities

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

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