In this online, self-learning activity:
Fabry disease is characterized by a deficiency of the glycoside hydrolase enzyme alpha galactosidase A, resulting in the accumulation of the glycolipid globotriaosylceramide throughout the body, particularly prominently in the blood vessels. A defect in the enzyme alpha galactosidase A results in glycosphingolipid accumulation, ultimately leading to multi-organ dysfunction and the patient’s premature death. Early symptoms, which occur during childhood, involve pain and may include Raynaud phenomenon, paresthesias, and arthralgia in the extremities and proximal limbs, as well as impaired gastrointestinal emptying, resulting in abdominal pain, diarrhea, early satiety, postprandial bloating, nausea, and vomiting. In adulthood, the disease’s impact spreads beyond and begins to affect the cardiac and renal systems.
The following healthcare professionals: cardiologists, nephrologists, pediatricians, and primary care physicians; physician assistants, nurse practitioners, nurses, and pharmacists; and any other healthcare professionals with an interest in or who may clinically encounter patients with Fabry disease.
Commercial Support Disclosure: This program is supported by an educational grant from Sanofi/Genzyme.
Learners may participate in this activity free of charge.
Release Date: August 13, 2020 -- Expiration Date: August 13, 2022
Faculty: Virginia Kimonis, M.D., MRCP -- Daisy Tapia,
Introduction to Fabry disease
Summary
By the end of the session the participant will be able to:
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Credit Designation: ScientiaCME designates this internet activity enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™ . Physicians should only claim credit commensurate with the extent of their participation in the activity.
ABIM MOC Recognition Statement: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
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Pharmacists
ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmaceutical education. This program is approved for 0.75 hours (0.075 CEUs) of continuing education. Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test. Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit. ACPE # 0574-0000-20-035-H01-P. CPE credit effective 8/13/20 and expires 8/13/22. This is a Application (A)-type activity.
Pharmacists: You must enter your NABP # and birth date correctly so that proof of participation can be posted to your NABP CPE profile. It is the learner's responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive CPE credit for this activity.
Nurse Practitioners (NPs): The American Academy of Nurse Practitioners accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME. ScientiaCME will provide NPs who successfully complete each activity with a certificate of participation indicating that the activity was designated for AMA PRA Category 1 Credit(s)™.
Physician Assistants: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.
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Faculty Disclosure:
Dr. Virginia E. Kimonis, MD, MRCP, Professor, Department of Pediatrics, Division of Genetic & Genomic Medicine, University of California, Irvine, is an advisory board member and has participated as a Primary Investigator in a registry supported by Sanofi Genzyme.
Daisy Tapia, MS, LCGC, Genetic Counselor, Clinical Instructor, University of California, Irvine, has no relevant conflicts of interest to disclose.
Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant conflicts of interest to disclose.
Disclosures of Peer Reviewer: Rob Hopkin, MD has received consulting income and research grants from Sanofi Genzyme, Amicus, Sangano, Avrobio, and Protalix
Disclosures of Peer Reviewer: George Sarka, MD has received consulting / speaker honorarium from Allergan
Commercial Support Disclosure: This program is supported by an educational grant from Sanofi/Genzyme.
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