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CME: Saving lives: New paradigms of care for opioid use disorder (OUD)

Activity Description / Statement of Need:

In this online CME self-learning program: Opioid use disorder (OUD) affects millions of individuals globally and is best defined by the DSM-5 as a condition due to tolerance, manifestation of physical dependence, and loss of control, which in turn leads to health hazards. The prevalence of OUD and the resultant impact on people is staggering, an estimated 130 people die from opioid overdoses every day. Moreover, the prevalence of OUD is increasing rapidly in concurrence with the widespread availability of opioids, with an estimated 60 prescriptions per 100 patients.

Professional societies, non-governmental organizations, and governmental agencies have all recommended a comprehensive public health approach to identifying and managing OUD, which will require the involvement of HCPs across specialties and regions. Implementing a comprehensive multidisciplinary cascade of care for patients with OUD will also necessitate that HCPs embrace new resources to deliver innovative and accessible health care. These resources may include novel prescription digital therapeutics, telemedicine, and engagement of non-physician HCPs who can provide support, counseling, and, in some cases, prescribing.

Target Audience:

Healthcare professionals specializing in: Addiction, pain management, primary care, family medicine, psychiatry; physician assistants, nurse practitioners, nurses, and pharmacists who practice in pain management or substance abuse; and any other health professionals who encounter OUD in the clinical setting.

This program is supported by an educational grant from Indivior.

Learners may participate in this activity free of charge.

Release Date: March 20, 2021 -- Expiration Date: March 20, 2023

Faculty: Michael Levine, MD


Faculty introduction, disclosures

Epidemiology of OUD

  • OUD trends
    • Increasing incidence
    • Concordance with opioid prescribing
  • Impact on patients and society
    • Morbidity and mortality
    • Cost
    • Health care resource use

Treatment of OUD

  • Therapeutic modalities
    • Cognitive behavioral therapy
    • Counseling
    • Pharmacotherapy
    • Prescription digital therapeutics
  • Medication-assisted treatment options
    • Methadone
    • Buprenorphine/naloxone
    • Naltrexone
    • Available formulations (e.g., oral, implant, injections)
  • Opioid detoxification and withdrawal
  • Individualizing treatments
    • Adult vs pediatric perspectives
    • Pregnancy
    • Incarceration
    • Patients suffering from acute or chronic pain
    • Intensive care unit and emergency departments
  • Best practices
    • Implementation and selection of treatment
    • Engaging multidisciplinary team
    • Improving access through novel technology
  • Patient case(s)

Summary, conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Describe the changing trends in OUD and the emerging roles for clinicians across specialties in identifying and managing OUD.
  • Evaluate recent efficacy and safety data for novel formulations of medication-assisted treatments for OUD, select patients who would benefit from long-acting formulations based on patient cases.
  • Identify challenges associated with the selection and implementation of drug regimens to the treatment of OUD and dependence, including risk factors for opioid overdose.
  • Develop strategies for recognizing and improving therapeutic adherence in patients treated for OUD and opioid dependence.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through ScientiaCME. ScientiaCME is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation: ScientiaCME designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™ toward the AMA Physician's Recognition Award. Physicians should only claim credit commensurate with the extent of their participation in the activity.


ABIM MOC Recognition Statement: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

PhysiciansFor maintenance of certification (MOC) credit, you must enter your board certification ID # and birth date correctly.  It is the learner's responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive MOC credit for this activity. Please note: Not all activities on this site provide MOC credit. If this activity does not specify that it provides MOC credit in this section, then it does NOT provide MOC credit.


ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 1.0 contact hours (0.1 CEUs) of continuing pharmacy education credit. Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test. Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit. ACPE # 0574-0000-21-006-H08-P. CPE credit effective 03/20/21 and expires 03/20/23. This is a Application (A)-type activity.

PharmacistsYou must enter your NABP # and birth date correctly so that proof of participation can be posted to your NABP CPE profile. It is the learner's responsibility to provide this information completely and accurately at the completion of the activity. Without providing it, the learner will NOT receive CPE credit for this activity.

Nurse Practitioners (NPs): The American Academy of Nurse Practitioners accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME. ScientiaCME will provide NPs who successfully complete each activity with a certificate of participation indicating that the activity was designated for AMA PRA Category 1 Credit(s)™.

Physician Assistants: The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME.

Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review ScientiaCME.

Faculty Disclosure: Michael Levine, MD, Department of Emergency Medicine, University of California, Los Angeles, has no relevant conflicts of interest to disclose.

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant conflicts of interest to disclose. 

Commercial Support Disclosure: This program is supported by an educational grant from Indivior.


  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowedge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Take the post-test
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural and Linguistic Competence

System Requirements

Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version

Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.

Additional Courses That Are Related To This Activity

Opioid dependence and opioid use disorder: Best practices, barriers in care, and the role of long-acting injectable medication

Updates in alcohol use disorder (AUD) pharmacotherapy and barriers to optimal care

Bipolar and mood disorder: Therapeutic updates and best practices

Addressing barriers to optimal care in schizophrenia with pharmacotherapy