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CME: Looking acne straight in the face: Treatment updates and challenges, with an emphasis on moderate to severe cases

ACCREDITATION EXPIRED: November 01, 2024

Activity Description / Statement of Need:

In this online, self-learning activity:

Acne is one of the most common skin conditions treated by physicians, affecting 40 to 50 million people in the U.S. Although the disease can affect patients at any age, acne occurs most commonly during the adolescent years, with a prevalence as high as 85%. In 20% of cases, the acne is severe, resulting in permanent physical scarring as well as a mental health burden. That burden may include increased prevalence of mood disorders, psychiatric hospitalizations, school absenteeism, unemployment, and suicidality.

Acne is a multifactorial inflammatory disease affecting the hair follicles of the skin. While an understanding of acne pathogenesis is one that is continuously evolving, key pathogenic factors include follicular hyper-keratinization, microbial colonization, sebum production, and complex immune and inflammatory mechanisms. Other research suggests that neuroendocrine regulatory mechanisms, diet, and genetic and factors all may contribute to the multifactorial process of acne pathogenesis. Professional guidelines for the treatment of acne vulgaris in adolescents and adults highlight the roles of topical and systemic pharmacotherapies as well as non-pharmacologic treatment modalities, including lasers and photodynamic therapy. However, in the time since the guidelines were published, newer medications have been approved or entered late stage clinical investigation. Communicating related information to HCPs in a timely manner is a demonstrated need.

Target Audience:

The following HCPs: dermatologists, primary care physicians, and pediatricians; nurse practitioners, physician assistants, and pharmacists who practice in dermatology and ambulatory care settings; and those who otherwise commonly care for or clinically encounter patients with acne.


Commercial Support Disclosure: This program is supported by an educational grant from Almirall, LLC.

This activity is free of charge.


Release Date: November 01, 2022 -- Expiration Date: November 01, 2024

Faculty: Charles Gropper, MD

Agenda

Faculty introduction, disclosures

Introduction content: Cursory refresher and review of acne

  • Epidemiology
  • Pathophysiologic principles with an eye on therapeutic targets
  • The healthcare burden posed by acne

Treatment of moderate to severe acne

  • When and whether to use systemic vs. topical therapy
  • Present pharmacotherapy, recent clinical evidence, and expert guidance

· Topical therapies: Retinoids, benzoyl peroxide, androgen receptor inhibition, dapsone

· Systemic therapy: isotretinoin, antibiotics, and hormonal agents

· Recent updates in available treatment options and novel agents

· Minimizing adverse effects

  • Emerging and future therapies
  • Considerations for specific patient populations: women, LGBTQ+
  • Adherence to therapy
  • Patient cases

Summary, conclusions, and best practice recap

Learning Objectives

By the end of the session the participant will be able to:

  • Summarize the healthcare burden experienced by patients with moderate to severe acne.
  • Recall presently available and emerging pharmacotherapeutic treatment strategies for moderate to severe acne and key factors that impact treatment decision-making.
  • Formulate a treatment plan for a patient with moderate or severe acne.
  • Describe challenges to the optimal treatment of acne and strategies for overcoming them.

Accreditation

ACCME Activity #202345340

ACCREDITATION FOR THIS COURSE HAS EXPIRED. YOU MAY VIEW THE PROGRAM, BUT CME / CE IS NO LONGER AVAILABLE AND NO CERTIFICATE WILL BE ISSUED.

Faculty Disclosure and Resolution of COI

As a provider of continuing medical education, it is the policy of ScientiaCME to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. In accordance with this policy, faculty and educational planners must disclose any significant relationships with commercial interests whose products or devices may be mentioned in faculty presentations, and any relationships with the commercial supporter of the activity. The intent of this disclosure is to provide the intended audience with information on which they can make their own judgments. Additionally, in the event a conflict of interest (COI) does exist, it is the policy of ScientiaCME to ensure that the COI is resolved in order to ensure the integrity of the CME activity. For this CME activity, any COI has been resolved thru content review by ScientiaCME.

Faculty Disclosure: Charles Gropper, MD, Clinical Associate Professor of Dermatology, Icahn School of Medicine at Mt. Sinai, has no relevant financial disclosures.

Disclosures of Educational Planners: Charles Turck, PharmD, BCPS, BCCCP, President of ScientiaCME, has no relevant financial disclosures.

Faculty will NOT discuss off-label uses.

All relevant financial relationships have been mitigated.

ScientiaCME adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Commercial Support Disclosure: This program is supported by an educational grant from Almirall.

Instructions

  • Read the learning objectives above
  • Take the Pre-Test (optional). Completion of the pre-test will help us evaluate the knowledge gained by participating in this CME activity.
  • View the online activity. You may view this is in more than one session, and may pause or repeat any portion of the presentation if you need to.
  • Minimum participation threshold: Take the post-test. A score of 70% or higher is required to pass and proceed to the activity evaluation.
  • Complete the activity evaluation and CME registration. A CE certificate will be emailed to you immediately.

Cultural/Linguistic Competence & Health Disparities

System Requirements

PC
Windows 7 or above
Internet Explorer 8
*Adobe Acrobat Reader
MAC
Mac OS 10.2.8
Safari or Chrome or Firefox
*Adobe Acrobat Reader
Internet Explorer is not supported on the Macintosh

*Required to view Printable PDF Version


Perform Pre-Test (optional)

Please take a few minutes to participate in the optional pre-test. It will help us measure the knowledge gained by participating in this activity.


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